ActiveDriverWGS 1.1.2

• Bug fixed: datasets with very few unmutated elements (<10) previously failed to include these elements in results.

ActiveDriverWGS 1.1.1

• Bug fixed: a rare set of very large elements with depletion of mutations would sometimes appear as enriched in mutations.

ActiveDriverWGS 1.1.0

Major Changes

• Alternative reference genomes for human (hg19, hg38) and mouse (mm9, mm10) are now supported. Default option is hg19.
• Full rewrite of ADWGS_rest for memory and speed efficiency.
• Improved handling on indels on boundaries of elements is now default. Removed parameter element_bias that controlled this behaviour earlier.
• README.rd and front page now include a simple example of running ActiveDriverWGS, and the vignette has been updated.
• Site IDs need to match element IDs. Example databases with PTM sites have been updated.